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Therefore, the use of topical steroids with high potency should not be practiced by nursing and breastfeeding motherswith severe systemic lupus erythematosus. If use of topical steroids is recommended, only those products with acceptable efficacy and/or safety should be used.Preconception and pregnancyUse of topical antiemetics during pregnancy should be discussed with the patient's physician. This information should be provided in the patient's usual medical record and the patient should be informed of the risks involved in using topical antiemetics during pregnancy.Use of topical steroid is contraindicated during pregnancy for any reason, including pre-eclampsia, placental abruption, fetal malformation, or maternal immunodeficiency syndrome.Erectile dysfunction during pregnancyWhen a patient is in menopause, topical steroids may decrease sexual desire and can be considered in cases of erectile dysfunction. Because of potential negative effects on semen production, there is a risk of decreased semen concentration with higher doses.Possible adverse effects to patients with erectile dysfunction include:Decreased libidoInsomniaDecreased sexual desireIncreased sexual desireDecreased orgasm sensitivityDecreased sexual excitementSexual side effects to women include:NauseaErectile dysfunctionIncreased risk of unintended pregnancy (abortion)Abdominal or pelvic painIn rare instances, the oral contraceptive pill may also affect sexual function due to its effects on hormonal function.Risks of pregnancy after use of topical steroidsAs with all drugs to be taken at any time, it is possible that topical steroid abuse in pregnancy carries some potential risks. However, no studies have been conducted to assess these risks in detail. To date, there are no animal studies on topical steroid use in pregnancy, so the potential risks for the fetus are unknown. It is also not known whether oral contraceptives can cause birth defects or fetal malformation in humans.There are few published data regarding the adverse effects of topical steroid exposure during pregnancy. As with other drugs to be taken before or during lactation, these are likely minor to moderate. A recent report by a study of pregnant women with a history of frequent steroid use, identified no adverse effects of topical steroid use in these women.References1. N. N. Cohen, S. L. Leung, K. M. Gao-Rice, M. V. Chua, VSimilar articles: